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Treatment

Mild restless legs syndrome that isn't linked to an underlying health condition can be managed with just a few lifestyle changes.

If symptoms are more severe, medication may be needed.

Restless legs syndrome caused by an underlying health condition can often be cured by treating that condition.

For example, iron deficiency anaemia can be treated by taking iron supplements.

If it's associated with pregnancy, it usually disappears on its own within 4 weeks of the birth.

Lifestyle changes

A number of lifestyle changes may be enough to ease the symptoms of restless legs syndrome.

These include:

  • avoiding stimulants in the evening (such as caffeine, tobacco and alcohol)
  • not smoking (read more about how to quit smoking)
  • regular daily exercise (but avoid exercising close to bedtime)
  • good sleep habits (tips to beat insomnia include going to bed and getting up at the same time every day, not napping during the day, taking time to relax before going to bed, and avoiding caffeine close to bedtime)
  • avoiding medicines that trigger the symptoms or make them worse (if you think medication is causing your symptoms, continue to take it and make an appointment to see your GP)

During an episode of restless legs syndrome, the following measures may help relieve your symptoms:

  • massaging your legs
  • taking a hot bath in the evening
  • applying a hot compress to your leg muscles
  • doing activities that distract your mind, such as reading or watching television
  • relaxation exercises, such as yoga or tai chi
  • walking and stretching
Medicine

Dopamine agonists

Dopamine agonists may be recommended if you're experiencing frequent symptoms of restless legs syndrome.

They work by increasing dopamine levels, which are often low.

Dopamine agonists that may be recommended include:

  • ropinirole
  • pramipexole
  • rotigotine skin patch

These medications can occasionally make you feel sleepy, so you should be cautious when driving or using tools or machinery after taking them.

Other possible side effects can include nausea or vomiting and dizziness.

Impulse control disorder (ICD) is a less common side effect sometimes associated with dopamine agonists.

People with ICD are unable to resist the urge to do something harmful to themselves or others.

For example, this could be an addiction to alcohol, drugs, gambling, shopping or sex (hypersexuality).

But the urges associated with ICD will subside once treatment with the dopamine agonist is stopped.

Painkillers

A mild opiate-based painkiller, such as codeine, may be prescribed to relieve pain associated with restless legs syndrome.

Gabapentin and pregabalin are also sometimes prescribed to help relieve painful symptoms of restless legs syndrome.

Side effects of these medications include dizziness, tiredness and headaches.

Medicines for aiding sleep

If restless legs syndrome is badly disrupting your sleep, a short-term course of medicine may be recommended to help you sleep.

These types of medicines are known as hypnotics, and include zopiclone and zolpidem.

Hypnotics are usually only recommended for short-term use (typically no longer than a week).

You may find you still feel sleepy or "hungover" the morning after taking your medicine.

Last Reviewed
12 January 2023
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Superintendent Pharmacist: Sanjay Majhu (GPhC No. 2052397)
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